Sanchez added another strikeout later in his no-decision. The Tigers eventually won, 5-4, in walk-off fashion on a Rajai Davis grand slam. Sanchez threw seven innings of eight-hit ball and allowed a pair of earned runs.
"Sanchie took us deep into the game. Can't ask for much more than that," said Tigers manager Brad Ausmus.
The 30-year-old right-hander now has 66 strikeouts this season after recording 202 last year. Sanchez also notched 202 strikeouts in 2011 with the Marlins.
"I knew they were going to be really aggressive," Sanchez said of facing the A's lineup. "They came in really hot. I just tried to put every pitch for a strike and take us deep into the game.
Matt Slovin is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.