Cueto's outing also marks the shortest postseason start in Reds history. The previous record was held by Joey Jay, who lasted two-thirds of an inning and gave up four runs on four hits, including a home run, to the Yankees in Game 5 of the 1961 World Series. The Reds lost the game, 13-5, and the series, 4-1.
Mat Latos, who tossed five innings in St. Louis on Tuesday, pitched on just three days' rest for the first time all season. Saturday also marked Latos' first relief appearance since he pitched for Class A Fort Wayne in the Midwest League in 2009.
This is the second time Brandon Phillips and Jay Bruce have homered in the same postseason game. They each hit solo homers off Philadelphia's Roy Oswalt in Game 2 of the NLDS on Oct. 8, 2010. The Reds built a 4-0 lead in that game, but eventually lost, 7-4.
Bruce is 8-for-15 lifetime against Matt Cain with three doubles, a home run and five RBIs.
The Reds are now 48-7 this season when Drew Stubbs scores a run.
Cain has surrendered multiple home runs in a game six times this season, two at AT&T Park. The Giants are 1-5 in those contests.
With his throwing error in the fourth inning, Scott Rolen has committed an error in three consecutive postseason games, dating to 2010, when he committed one in both Games 2 and 3 of the NLDS against the Phillies. Prior to that, Rolen's last postseason error came in Game 1 of the 2006 World Series when he was with the Cardinals.
The Giants had not lost a Division Series opener since 1997.
The only other time a 2-3 playoff format was used in the NLDS from 1995-97, the road team has won the series opener five times. Those teams have won the series four times.
Mark Clements is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.